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Tuberculosis screening with Aeonose and CAD4TB® in Paraguayan prisons

Tuberculosis in Paraguay

Tuberculosis is one of the main causes of death by infectious diseases in Paraguay. Tuberculosis is especially prevalent in crowded places with poor living conditions and bad ventilation. Prisons are an example of such places. The prevalence of TB in Paraguayan prisons is estimated to be 100 times higher than the national prevalence. 

The research

The aim of the World Health Organization (WHO) "End TB Strategy" is to end the global pandemic by 2035. If we want to achieve that, we need better diagnostic techniques to improve screening of high-risk populations.


This study researches TB the AeoNose™ (an electronic nose device) and CAD4TB® (chest X-ray with computed automated detection) in a specific high-risk population: prisons in Paraguay. The study population will consist of prisoners and prison employees. 

After providing informed consent, this study will systematically screen prisoners and its employees for TB, with the AeoNose™ and CAD4TB® and compare them with the gold standard for TB, a mycobacterial culture. 

You'll find a video about the procedure of the informed consent here.

For more information, see the registration of this trial in by clicking here.

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